Kisspeptin-10
Price range: £45.00 through £65.00
CAS: 374675-21-5
Strengths Available: 10mg
Format: Sealed containment / vial presentations available
Volume: 3mL
What is Kisspeptin-10 about?
KISSPEPTIN 10 is a research-grade peptide studied in the context of reproductive and hormonal-signalling research. Investigators have explored how KISSPEPTIN 10 interacts with receptors and pathways involved in reproductive and endocrine regulation in laboratory models.
Description
What is Kisspeptin-10?
KISSPEPTIN 10 is a research-grade peptide studied in the context of reproductive and hormonal-signalling research.
Investigators have explored how KISSPEPTIN 10 interacts with receptors and pathways involved in reproductive and endocrine regulation in laboratory models.
Why Researchers Became Interested?
Researchers became interested in KISSPEPTIN 10 because of its relevance to reproductive and hormonal-signalling research. It provides a defined research tool for examining endocrine
pathways in experimental models.
Key Research Focus Areas
- Reproductive and endocrine signalling models
- Hormonal-axis regulation studies
- Receptor-binding and pathway investigations
- Behavioural and neuroendocrine research
- Sexual-health research models
- Hypothalamic–pituitary signalling research
What the Research Has Shown
In preclinical research, KISSPEPTIN 10 has been studied for its influence on reproductive and hormonal-signalling pathways.
Mechanistic studies have explored its interaction with receptors central to endocrine regulation.
Scientific Background and Research Context
Kisspeptin is a naturally occurring neuropeptide encoded by the KISS1 gene. It binds to the kisspeptin receptor, also known as KISS1R or GPR54, and is best known for its central role in regulating the hypothalamic-pituitary-gonadal axis, or HPG axis. In reproductive endocrinology, kisspeptin is studied because it acts upstream of gonadotropin-releasing hormone, commonly known as GnRH, which then regulates the release of LH and FSH from the pituitary gland.
Kisspeptin attracted major scientific attention because it is considered one of the key gatekeepers of reproductive hormone signalling. Research has shown that kisspeptin stimulates GnRH neurons, leading to downstream activation of LH and FSH secretion. This makes the kisspeptin system highly relevant to studies of puberty, fertility, reproductive hormone feedback, menstrual-cycle regulation, and gonadal function.
Exploring the Science Behind the Kisspeptin-GnRH Pathway
The kisspeptin-GnRH pathway is central to modern reproductive biology. Kisspeptin neurons communicate with GnRH neurons in the hypothalamus. GnRH then travels to the anterior pituitary, where it stimulates gonadotroph cells to release LH and FSH. These hormones regulate ovarian and testicular function, including steroid hormone production and gamete development.
Kisspeptin neurons are also involved in sex-steroid feedback. This means they help the body respond to changing levels of oestrogen, progesterone, and testosterone. Because of this, kisspeptin is studied as an important link between the brain, endocrine system, and reproductive organs.
Research Context in Reproductive and Endocrine Science
Kisspeptin has been investigated in several areas of reproductive research, including:
- puberty onset and reproductive maturation
- hypothalamic amenorrhoea
- hypogonadotropic hypogonadism
- infertility and assisted reproduction
- LH pulsatility and ovulation signalling
- sex-steroid feedback mechanisms
- polycystic ovary syndrome-related hormone regulation
Early human studies suggest that peripheral kisspeptin administration can stimulate gonadotrophin release in healthy adults and in some patient groups, which supports its role as a research tool for studying HPG-axis responsiveness.
Ongoing Scientific Interest
Kisspeptin remains a major research focus because it sits at a critical control point in reproductive hormone regulation. Unlike compounds that act directly at the ovary, testes, or pituitary, kisspeptin acts higher in the neuroendocrine pathway, making it useful for studying how the brain controls reproductive function.
Current scientific interest also includes kisspeptin analogues, clinical reproductive research, and potential applications in assisted reproduction. Reviews of clinical research note that kisspeptin and related analogues have been studied for their ability to regulate GnRH and LH secretion, with clinical trials exploring safety and reproductive-health applications.
Overall, kisspeptin is best understood as a key neuroendocrine signalling peptide involved in GnRH activation, LH/FSH regulation, puberty, fertility, and reproductive-axis research.
For research and laboratory use only. Not for human or veterinary use.
Formats Available
| Format | Volume | Strength | Purity | Description |
| Sealed containment / vial presentations available | 3ml | 5mg | >99% | Precision 60-click sealed-containment delivery system |
Ingredient Profile
Single research compound: Kisspeptin-10. CAS: 374675-21-5. Purity >99%. Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
Kisspeptin-10 — 10mg
Ingredient Breakdown
Kisspeptin-10: 10mg of active peptide per vial (lyophilised).
Why is KISSPEPTIN studied in hormonal-signalling research?
Because studies have explored its relevance to reproductive and hormonal-signalling pathways.
Is KISSPEPTIN 10 approved for medical use?
No. It is supplied strictly for research and laboratory use only, and is not intended for human or veterinary use.
Why does purity matter so much for this product?
High purity helps ensure that observed research effects are due to the material itself rather than impurities.
What does ‘research grade’ mean?
It means the product is supplied with documentation and traceability for laboratory investigation.
Is international supply available?
Yes. International fulfilment and temperature controlled shipping can be supported where appropriate.
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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