KPV
Price range: £10.00 through £38.00
CAS Number: 67763-96-6
Strengths Available: 5mg / 10mg
Format: Sealed containment / vial presentations available
Volume: 3mL
What KPV Is About
KPV is a short tripeptide derived from alpha-melanocyte-stimulating hormone (α-MSH) that has attracted attention in scientific literature for its role in inflammatory modulation and epithelial barrier research.
Because of its compact structure and targeted signalling profile, KPV has become a subject of interest in studies exploring immune responses, gut integrity, and skin barrier biology.
Description
What is KPV?
In simple terms, KPV is a small signalling peptide that helps researchers understand how the body controls inflammation and protects tissue barriers.
Rather than acting broadly across the immune system, KPV is studied for its more targeted interaction with inflammatory signalling pathways.
Why Researchers Study KPV
- Investigation of inflammatory modulation pathways
- Study of epithelial and gut barrier integrity
- Exploration of immune-signalling regulation
- Research into skin and mucosal biology
- Examination of targeted peptide signalling mechanisms
What the Research Has Shown
Research literature has explored KPV’s interaction with inflammatory mediators such as cytokines and its role in regulating immune responses in experimental models.
Additional studies have examined its effects on epithelial barrier function, particularly in gastrointestinal and skin-related
research contexts. These observations describe biological effects explored in research environments and do not constitute approved medical or therapeutic claims.
Scientific Background and Research Context
KPV is a short tripeptide corresponding to the C-terminal amino-acid sequence of alpha-melanocyte-stimulating hormone (α-MSH). Researchers are interested in KPV because this minimal sequence retains some of the anti-inflammatory activity associated with the larger α-MSH molecule. Current evidence remains primarily preclinical, based on laboratory and animal studies. PubMed
Exploring the Science Behind
Experimental research has examined KPV’s interaction with inflammatory pathways and intestinal peptide transport. In cellular and mouse models, KPV uptake through the peptide transporter PepT1 was associated with reduced inflammatory responses. Researchers have also investigated its effects on inflammatory cytokine expression and experimental intestinal inflammation. These findings require confirmation in controlled human studies. PubMed
Research Context in Endocrine and Metabolic Science
Because KPV is derived from α-MSH, it is studied within the broader melanocortin system—a network involved in endocrine signalling, immune regulation, pigmentation and energy homeostasis. Unlike research focused on the full hormone, KPV studies have concentrated mainly on inflammatory and immune-related mechanisms rather than direct hormonal or metabolic effects.
Ongoing Scientific Interest
KPV remains a subject of interest in experimental inflammation, intestinal biology and peptide-delivery research. Scientists are evaluating targeted delivery systems designed to improve its stability and localisation in laboratory models. However, clinical efficacy, long-term safety, pharmacokinetics and appropriate human dosing have not been established. KPV should therefore be presented as a research compound rather than an approved medical treatment. PubMed Central
Ingredient Profile
Single research compound: KPV.
CAS: 67763-96-6. Purity >99%.
Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
KPV — 5mg / 10mg
Ingredient Breakdown
KPV: 5mg / 10mg of active peptide per vial (lyophilised).
What does KPV stand for?
KPV refers to the amino acid sequence Lysine–Proline–Valine, derived from α-MSH.
Is KPV a steroid or hormone?
No. KPV is a short peptide studied for signalling effects in inflammatory pathways.
Why is KPV studied in gut and skin research?
Because it has been examined for its role in epithelial barrier integrity and immune modulation.
Is KPV an anti-inflammatory drug?
No. It is supplied strictly for research and laboratory investigation only.
Why is KPV often included in peptide combinations?
Because it complements repair-focused peptides by addressing inflammatory signalling pathways.
Does KPV suppress the immune system?
Research focuses on modulation rather than suppression, depending on experimental context.
Why does purity matter for KPV research?
High purity helps ensure that observed research effects are due to the material itself rather than impurities.
What does ‘research grade ‘ mean?
It means the product is supplied with documentation and traceability for laboratory investigation.
Is international supply available?
Yes. International fulfilment and temperature-controlled shipping can be supported where appropriate.
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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