MOTS-c

Price range: £22.00 through £86.00

CAS Number: 1628316-13-6

Strengths Available: 10mg /30mg/ 40mg
Format: Sealed containment / vial presentations available
Volume: 3mL

What This Product Is About

MOTS-c is a mitochondrial-derived peptide that has become an area of growing interest in metabolic, mitochondrial, and cellular energy research.
Unlike many peptides that originate from nuclear DNA, MOTS-c is encoded within mitochondrial DNA, making it particularly relevant to studies examining cellular energy regulation and metabolic signalling.

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Description

What Is MOTS-c?
In simple terms, MOTS-c is a signalling peptide produced by mitochondria, the energy-producing structures within cells.
Researchers study MOTS-c to better understand how cells sense energy availability and respond to metabolic stress.

Why Researchers Study MOTS-c

  • Investigation of mitochondrial signalling pathways
  • Study of cellular energy regulation and metabolism
  • Exploration of insulin sensitivity and glucose utilisation
  • Research into stress-response and adaptive signalling
  • Examination of mitochondrial–nuclear communication

What the Research Has Shown
Research literature has demonstrated that MOTS-c participates in cellular responses to metabolic stress and energy imbalance in experimental models. Studies have explored its role in glucose metabolism, insulin signalling, and exercise-related adaptation pathways. These observations describe biological mechanisms explored in research environments and do not constitute approved medical, metabolic, or performance claims.

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Scientific Background and Research Context of MOTS-c

MOTS-c is a mitochondria-derived peptide studied for its role in cellular energy regulation, metabolic signalling, and stress-response pathways. Unlike many peptides that originate from nuclear DNA, MOTS-c is encoded within mitochondrial DNA, making it especially interesting in research focused on mitochondrial function and metabolic health.

Exploring the Science Behind MOTS-c

MOTS-c is closely linked to the way cells sense and respond to energy demand. Research has explored its influence on glucose metabolism, insulin sensitivity, AMPK signalling, and cellular adaptation under metabolic stress.

Because mitochondria are central to ATP production, oxidative balance, and nutrient utilisation, MOTS-c has become an important research peptide in studies examining how mitochondrial signals communicate with the rest of the cell.

Research Context in Metabolic and Body-Composition Science

In metabolic research, MOTS-c is studied for its potential relevance to energy balance, glucose handling, fat metabolism, and age-related metabolic changes. Scientific interest has also focused on how MOTS-c may influence skeletal muscle metabolism, exercise adaptation, and cellular resilience.

Its connection to AMPK signalling makes it particularly relevant in studies of nutrient sensing, mitochondrial efficiency, and metabolic flexibility.

Ongoing Scientific Interest

MOTS-c remains an active area of investigation because it represents a link between mitochondrial genetics, cellular energy control, and whole-body metabolic regulation.

Overall, MOTS-c is best understood as a mitochondria-derived research peptide used to study metabolic signalling, energy balance, mitochondrial communication, and body-composition-related pathways.

For research and laboratory use only. Not for human or veterinary use.

Ingredient Profile
Single research compound: MOTS-c
CAS: 1628316-13-6
Purity >99%
Supplied as lyophilised powder (no excipients, fillers or additives).

Active Ingredients
MOTS-c — 10 / 30 / 40mg

Ingredient Breakdown
MOTS-c: 10 / 30 / 40mg of active peptide per vial (lyophilised).

What does MOTS-c stand for?
MOTS-c refers to a mitochondrial open-reading- frame-derived peptide.

Why is MOTS-c considered unique among peptides?
Because it is encoded by mitochondrial DNA rather than nuclear DNA.

Is MOTS-c related to energy metabolism?
Yes. It is studied for its role in cellular energy sensing and metabolic regulation.

Is MOTS-c a hormone?
No. It is a signalling peptide studied in research settings.

Why is MOTS-c discussed in exercise research?
Because studies have examined its involvement in metabolic adaptation pathways.

Is MOTS-c approved for medical use?
No. It is supplied strictly for research and laboratory use only, and is not intended for human or veterinary use.

Why does purity matter so much for this product?
High purity helps ensure that observed research effects are due to the material itself rather than impurities.

What does ‘research grade ‘ mean?
It means the product is supplied with documentation and traceability for laboratory investigation.

Is international supply available?
Yes. International fulfilment and temperature-controlled shipping can be supported where appropriate.

 

 

Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.

Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.

Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.

For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.

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