CJC-1295 (with DAC)
Price range: £30.00 through £50.00
CAS No: 863288-34-0
Strengths Available: 5mg
Format: Sealed containment device with precision 300-click/ vial presentations available
Volume: 3mL
What Is CJC-1295 with DAC?
CJC-1295 with DAC is widely discussed in research settings as a long-acting analogue of Growth Hormone Releasing Hormone (GHRH). Rather than supplying growth hormone directly, it is used to study how the body releases its own growth hormone over extended periods.
The defining feature of this version is the Drug Affinity Complex (DAC), which allows the molecule to bind to blood proteins. This binding significantly extends its activity window, making it especially useful for studying sustained growth hormone signalling.
Description
What Is CJC 1295 ?
CJC 1295 Is a research-grade peptide studied in the
context of growth hormone secretagogue and GH-axis signalling research. Investigators have explored how CJC 1295 No DAC interacts with receptors and pathways involved in the regulation of growth hormone and downstream IGF activity.
Why Researchers Study CJC-1295 with DAC
- To explore sustained endogenous growth hormone release
- To study downstream markers such as IGF-1 under prolonged
signalling conditions - To compare long-acting versus short-acting growth hormone
release patterns - To better understand growth hormone regulation without
bypassing natural feedback systems.
Why It Is Commonly Researched Alongside
CJC-1295 with DAC is frequently discussed alongside Ipamorelin in the scientific literature. This is because the two compounds stimulate growth hormone release through complementary biological pathways.
CJC-1295 acts via the GHRH receptor, while Ipamorelin works through the ghrelin receptor. Together, they allow researchers to examine growth hormone signalling from multiple angles.
What the Research Has Shown
Preclinical and clinical-stage research has demonstrated that CJC-1295 with DAC can significantly increase circulating growth hormone levels and downstream markers such as IGF-1
in experimental settings. Because of its extended half-life, the DAC version is associated with more sustained growth hormone signalling than non-
DAC variants. These findings describe biological signalling patterns rather than therapeutic outcomes.
Scientific Background and Mechanism of Action
CJC-1295 with DAC contains a Drug Affinity Complex linker that enables reversible binding to serum albumin. This modification significantly prolongs the half-life of the peptide (up to 6–8 days in some models), allowing for sustained GH release with fewer administrations. It stimulates the pituitary gland to release endogenous GH, which in turn activates hepatic IGF-1 production and anabolic pathways. Unlike the short-acting No DAC form, CJC-1295 with DAC provides steady-state GH elevation without disrupting feedback in controlled conditions.
This extended duration makes CJC-1295 with DAC a valuable research compound for studying chronic GH axis stimulation, endocrine adaptation, and metabolic homeostasis. It is frequently used alongside other pituitary modulators to compare pulsatile versus sustained hormonal patterns in experimental settings.
Comparison and Synergy with Other Peptides
CJC-1295 with DAC is often compared to its No DAC variant to assess the impact of release kinetics on GH axis function. While the No DAC form produces rapid GH pulses, the DAC variant maintains elevated GH levels over longer periods. In combination with Ipamorelin, it creates a dual mechanism model — a sustained baseline from CJC and amplitude enhancement from the ghrelin pathway. This synergy enables research into receptor sensitisation, feedback loops, and long-term anabolic responses in controlled endocrine experiments.
Ingredient Profile
Single research compound: CJC-1295 (with DAC). CAS: 863288-34-0. Purity >99%. Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
CJC-1295 (with DAC) — 5mg
Ingredient Breakdown
CJC-1295 (with DAC): 5mg of active peptide per vial (lyophilised).
What is the difference between CJC-1295 No-DAC and the DAC version?
The No-DAC version is short acting and produces brief growth hormone pulses, while the DAC version produces prolonged signalling.
Why would researchers prefer the No-DAC version?
Because it allows study of hormone release patterns that more closely resemble natural physiological pulses.
Is this growth hormone?
No. It stimulates the body to release its own growth hormone.
Why is it often paired with Ipamorelin?
Because both support pulse-based growth hormone release through complementary pathways.
Why is it still studied today?
Because it offers insight into how repair and recovery processes function at a biological level.
Does it act like a hormone or growth factor?
No. It appears to influence repair pathways without acting as a classical hormone.
Why does purity matter so much for this peptide?
High purity helps ensure that observed research effects are due to the peptide itself rather than impurities.
What does ‘research grade’ mean?
It means the product is supplied with documentation and traceability for laboratory investigation.
What is the sealed containment device used for?
It provides a consistent analytical reference system for laboratory measurement.
Is international supply available?
Yes. International fulfilment and temperature‐controlled shipping can be supported where appropriate
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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