Colivelin
CAS No: 867021-83-8
Strengths Available: 5mg/10mg
Format: Sealed containment / vial presentations available
Volume: 3 mL
What This Product Is About
Colivelin is an experimental neuroprotective peptide developed mainly for neuroscience research. It has attracted interest because of its ability to influence pathways associated with neuronal survival and cellular stress responses.
Description
What Is Colivelin?
Colivelin is a synthetic peptide that acts as a STAT3 activator and has demonstrated neuroprotective activity in laboratory and animal studies. It has been investigated particularly in models involving amyloid-beta toxicity, memory impairment and brain injury.
Why Researchers Became Interested in Colivelin
Researchers became interested in Colivelin because it showed the ability to protect neurons from different forms of cellular damage and to influence signalling pathways involved in neuronal survival.
Key Research Focus Areas
- Neuroprotection
- Alzheimer’s disease models
- Memory and cognition
- STAT3 signalling
- Amyloid-beta toxicity
- Ischemic brain injury
- Neuronal survival
What the Research Has Shown
Preclinical studies have shown that Colivelin can reduce neuronal death, protect against amyloid-beta-related toxicity and improve memory or neurological outcomes in several experimental models. Most evidence remains laboratory or animal-based.
Scientific Background and Research Context
Colivelin is a synthetic hybrid peptide combining elements of Humanin and activity-dependent neurotrophic factor (ADNF), developed for neuroprotective research. (PubMed)
Exploring the Science Behind
Research focuses on its ability to influence cell-survival pathways, including STAT3 and CaMKIV signalling, and protect neurons from cellular stress.
Research Context in Endocrine and Metabolic Science
Colivelin is mainly investigated in neuroscience, mitochondrial function, cellular stress and neurodegenerative-disease research.
Ongoing Scientific Interest
Scientific interest centres on its potential role in neuronal survival, cognitive function and protection against neurodegenerative processes.
Ingredient Profile
Single research compound: Colivelin
CAS: 867021-83-8
Purity >99%
Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
Colivelin— 5 mg / 10 mg
Ingredient Breakdown
Colivelin: 5 mg / 10 mg of active peptide per vial (lyophilised).
Why is Colivelin studied in metabolic research?
Colivelin is more commonly studied in neuroscience and cellular signalling research than general metabolic research. Its main areas of interest involve neuronal survival, oxidative stress and STAT3-related pathways.
Is Colivelin approved for medical use?
No. Colivelin remains an experimental research peptide and is not an approved medicine for routine human treatment.
Why does purity matter so much for this product?
High purity helps reduce unwanted peptide fragments and synthesis-related impurities that could interfere with experimental results.
What does “research grade” mean?
Research grade means the material is intended for laboratory or analytical research. It does not mean the product is pharmaceutical grade or approved for human administration.
Is international supply available?
International availability depends on the supplier, destination country and regulations governing the import and distribution of research peptides.
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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