FGL
CAS No: 499993-62-3
Strengths Available: 5mg/10mg/20mg
Format: Sealed containment / vial presentations available
Volume: 3 mL
What This Product Is About
FGL is a synthetic 15-amino-acid peptide derived from the neural cell adhesion molecule (NCAM). It was developed mainly for neuroscience research involving neuronal signalling, plasticity and regeneration.
Description
What Is FGL?
FGL is an NCAM-derived fibroblast growth factor receptor (FGFR) agonist. It interacts with FGFR, particularly FGFR1, and activates signalling pathways associated with neuronal growth and survival.
Why Researchers Became Interested in FGL
Researchers became interested in FGL because NCAM-FGFR signalling plays an important role in neuronal development, synaptic plasticity and neural repair.
FGL provides a research tool for investigating these pathways without using the complete NCAM protein.
Key Research Focus Areas
- Neuroplasticity
- Memory and cognition
- FGFR1 signalling
- Neuronal survival
- Neurogenesis
- Synaptic development
- Stroke and neural regeneration
- Neurodegenerative disease models
What the Research Has Shown
Preclinical studies have shown that FGL can stimulate neurite growth and neuronal survival and influence FGFR-related signalling. Animal studies have also investigated its effects on cognition, neuroprotection and regeneration following neurological injury.
Most evidence remains preclinical, so these findings should not be interpreted as established therapeutic effects in humans.
Scientific Background and Research Context
FGL is a synthetic peptide derived from neural cell adhesion molecule (NCAM) and studied for its interaction with fibroblast growth factor receptors.
Exploring the Science Behind
Research focuses on how FGL activates FGFR1 signalling and influences neuronal growth and survival.
Research Context in Endocrine and Metabolic Science
FGL is primarily investigated in neuroscience, cellular signalling and neuroplasticity research rather than classical endocrine research.
Ongoing Scientific Interest
Scientific interest centres on its potential effects on neuronal development, synaptic function and neuroprotective pathways.
Ingredient Profile
Single research compound: FGL
CAS: 499993-62-3
Purity >99%
Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
FGL— 5 mg / 10 mg / 20 mg
Ingredient Breakdown
FGL: 5 mg / 10 mg / 20 mg of active peptide per vial (lyophilised).
Why is FGL studied in metabolic research?
FGL is more accurately associated with neuroscience and cellular signalling research than general metabolic research. Researchers study how FGFR signalling affects neuronal survival, plasticity and regeneration.
Is FGL approved for medical use?
No. FGL is an investigational research peptide and is not an approved medicine for routine human treatment. Current evidence is predominantly from laboratory and animal research.
Why does purity matter so much for this product?
High purity helps reduce the presence of incomplete peptide sequences, synthesis by-products and contaminants that could interfere with research results.
What does “research grade” mean?
Research grade means the material is intended for laboratory or analytical research. It does not mean the product is pharmaceutical grade or approved for human administration.
Is international supply available?
International supply depends on the supplier, destination country and local regulations governing the import and distribution of research peptides.
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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