GDF11
CAS No: 867021-83-8
Strengths Available: 5mg/10mg
Format: Sealed containment / vial presentations available
Volume: 3 mL
What This Product Is About
Colivelin is an experimental neuroprotective peptide developed mainly for neuroscience research. It has attracted interest because of its ability to influence pathways associated with neuronal survival and cellular stress responses.
Description
What Is GDF11?
GDF11 is a secreted growth factor that signals through activin receptors and influences SMAD2/3 pathways, which regulate cellular development and tissue function.
Why Researchers Became Interested in GDF11
Researchers became interested in GDF11 because of its possible roles in aging, tissue regeneration, cardiovascular biology and nervous-system function.
Key Research Focus Areas
- Aging biology
- Tissue regeneration
- Muscle research
- Cardiovascular function
- Brain and neurological research
- Stem and progenitor cells
- TGF-β/SMAD signalling
What the Research Has Shown
Preclinical studies suggest GDF11 may influence vascular remodelling, tissue development and cellular regeneration. However, its role in aging and rejuvenation remains an active and sometimes conflicting area of research.
Scientific Background and Research Context
GDF11 (Growth Differentiation Factor 11) is a naturally occurring protein belonging to the TGF-β superfamily, involved in tissue development and cellular signalling. (PubMed)
Exploring the Science Behind
Research explores how GDF11 influences SMAD signalling, tissue regeneration, muscle biology and metabolic processes. (PubMed)
Research Context in Endocrine and Metabolic Science
GDF11 has been studied in relation to ageing, skeletal muscle, cardiovascular function, bone biology and metabolism. (PubMed)
Ongoing Scientific Interest
Scientific interest continues around GDF11’s role in age-related biology and tissue regeneration, although some of its effects remain debated. (PubMed)
Ingredient Profile
Single research compound: GDF11
CAS: No single universally used CAS number is consistently assigned to recombinant GDF11 protein. Identification is commonly based on GDF11 / BMP11, Gene ID 10220, and UniProt O95390.
Purity >99%
Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
GDF11 — 10 ug / 20 ug
Ingredient Breakdown
GDF11: 10 ug / 20 ug of active peptide per vial (lyophilised).
Why is GDF11 studied in metabolic research?
GDF11 is studied because it participates in signalling pathways involved in tissue growth, development, metabolism and age-related biological changes.
Is GDF11 approved for medical use?
No. Recombinant GDF11 is primarily a research protein and is not approved as a routine therapeutic medicine.
Why does purity matter so much for this product?
High purity helps ensure reliable experimental results and reduces interference from unwanted proteins or production-related contaminants.
What does “research grade” mean?
Research grade means the material is intended for laboratory and analytical research, not automatically for human administration.
Is international supply available?
International supply depends on the supplier, destination country and local regulations governing research proteins and biological materials.
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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