HEP-1
CAS No: 174641-44-2
Strengths Available: 10/20/30 mg
Format: Sealed containment / vial presentations available
Volume: 3mL
What This Product Is About
HEP-1 is a synthetic 14-amino-acid peptide corresponding to amino acids 324–337 of the human ezrin protein. It has mainly attracted research interest for its potential antiviral, anti-inflammatory and immunomodulatory properties.
Description
What is HEP-1?
HEP-1 is an ezrin-derived peptide investigated for its ability to influence immune responses, inflammation and adaptive antiviral immunity.
Why Researchers Became Interested in HEP-1
Researchers became interested in HEP-1 because ezrin participates in immune-cell signalling. Experimental and early clinical research suggested that HEP-1 may influence inflammatory responses and antibody-mediated immunity.
Key Research Focus Areas
- Antiviral research
- Immune modulation
- Inflammatory signalling
- B-cell and T-cell responses
- Antibody production
- Respiratory viral infections
- HIV and hepatitis research
What the Research Has Shown
Laboratory and limited clinical studies have investigated HEP-1 in viral infections and immune regulation. Research has reported effects on inflammatory signalling and antibody responses, but broader controlled studies are needed to establish clinical effectiveness.
Scientific Background and Research Context
HEP-1, also known as Human Ezrin Peptide 1, is a synthetic peptide consisting of 14 amino acids. It mimics amino acids 324–337 within a region of the human ezrin protein. Ezrin helps connect the cell membrane to the internal cytoskeleton and participates in cellular signalling, immune-cell movement and immune activation. Researchers are studying whether HEP-1 can influence these processes and modify immune responses. [Published review](https://pmc.ncbi.nlm.nih.gov/articles/PMC8584018/)
Exploring the Science Behind
Research has examined HEP-1’s potential effects on both innate and adaptive immunity. Proposed mechanisms include influencing immune-cell signalling, supporting B-cell and antibody-related responses, and regulating inflammatory cytokines. Its antiviral effects may therefore arise from modifying the host immune response rather than directly destroying viruses. However, these mechanisms remain under investigation and are not yet fully established.
Research Context in Endocrine and Metabolic Science
HEP-1 is primarily associated with immunology, virology and inflammation research. It is not considered a classical endocrine peptide because it is not known to act directly as a hormone or regulate a specific endocrine gland. Any relevance to metabolic science is currently indirect, mainly through the relationship between immune signalling, chronic inflammation and metabolic health.
Ongoing Scientific Interest
Current scientific interest centres on HEP-1’s potential antiviral, anti-inflammatory and immune-modulating properties. Researchers have explored it in relation to viral infections and inflammatory conditions, including a registered clinical study involving SARS-CoV-2. Important research questions remain regarding its precise mechanism, effective dosing, stability, safety and clinical usefulness. The available evidence is still limited, so research findings should not be interpreted as proof of established therapeutic benefit.
Ingredient Profile
Single research compound: HEP-1
CAS: 174641-44-2
Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
HEP-1— 10/20/30 mg
Ingredient Breakdown
HEP-1 : 10/20/30mg of active peptide per vial (lyophilised).
Why is HEP-1 studied in metabolic research?
HEP-1 is more accurately associated with immunology, inflammation and antiviral research than general metabolic research.
Is HEP-1 approved for medical use?
HEP-1 is not FDA- or EMA-approved for routine medical use. A formulation known as Gepon has been reported as registered for human use in Russia, while HEP-1 remains investigational in many other jurisdictions.
Why does purity matter so much for this product?
High purity helps reduce unwanted peptide fragments and synthesis-related impurities that could interfere with research results.
What does “research grade” mean?
Research grade means the material is intended for laboratory or analytical research and does not automatically mean it is pharmaceutical grade or suitable for human use.
Is international supply available?
International availability depends on the supplier, destination country and applicable regulations governing research peptides and biological materials
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
Partner with FreshstartPharma– Where Accuracy Meets Innovation
Freshstartpharma is committed to delivering high-quality research-grade products designed for advanced scientific applications. We offer wholesale partnerships to selected businesses that share our values of integrity, quality, and innovation. Whether you’re an established distributor or an emerging research supply company, we invite you to join our network and benefit from exclusive access to our state-of-the-art product range.
