Protirelin
CAS No: 24305-27-9
Strengths Available: 10 mg
Format: Sealed containment / vial presentations available
Volume: 3mL
What This Product Is About
Protirelin is a synthetic tripeptide analogue of naturally occurring thyrotropin-releasing hormone (TRH). It is primarily associated with endocrine and thyroid research.
Description
What Is Protirelin?
Protirelin is a three-amino-acid peptide that stimulates the anterior pituitary to release thyroid-stimulating hormone (TSH) and prolactin
Why Researchers Became Interested in Protirelin
Researchers became interested in Protirelin because TRH plays a central role in the hypothalamic-pituitary-thyroid axis, making it useful for investigating thyroid regulation and pituitary function.
Key Research Focus Areas
- Thyroid hormone regulation
- TSH secretion
- Pituitary function
- TRH receptor signalling
- Prolactin secretion
- Hypothalamic-pituitary signalling
- Endocrine disorders
What the Research Has Shown
Research has established that Protirelin can stimulate TSH and prolactin release, making it useful for studying pituitary and thyroid-axis responses. It has historically been used in the TRH stimulation test.
Scientific Background and Research Context
Protirelin is a synthetic form of thyrotropin-releasing hormone (TRH), a naturally occurring tripeptide involved in hypothalamic-pituitary signalling.
Exploring the Science Behind
Research focuses on how protirelin stimulates the release of thyroid-stimulating hormone (TSH) and prolactin from the pituitary gland.
Research Context in Endocrine and Metabolic Science
Protirelin is studied in thyroid regulation, pituitary function and hypothalamic-pituitary endocrine signalling.
Ongoing Scientific Interest
Scientific interest continues around its role in endocrine testing, hormone regulation and neuroendocrine research.
Ingredient Profile
Single research compound: Protirelin
CAS: 24305-27-9
Supplied as lyophilised powder (no excipients, fillers or additives).
Active Ingredients
Protirelin — 10 mg
Ingredient Breakdown
Protirelin : 10 mg of active peptide per vial (lyophilised).
Why is Protirelin studied in metabolic research?
Protirelin is studied because thyroid hormones strongly influence energy expenditure, metabolism and endocrine regulation, while TRH controls an important upstream part of this system.
Is Protirelin approved for medical use?
Protirelin has been used clinically as a diagnostic agent, but there is currently no FDA-approved protirelin product in the United States. Regulatory availability varies by country.
Why does purity matter so much for this product?
High purity helps reduce unwanted peptide fragments and synthesis-related impurities that could interfere with receptor signalling and experimental results.
What does “research grade” mean?
Research grade means the material is intended for laboratory or analytical research and does not automatically mean it is pharmaceutical grade or suitable for human administration.
Is international supply available?
International availability depends on the supplier, destination country and applicable regulations governing research peptides and diagnostic substances.
Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.
Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.
Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.
For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.
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