Abaloparatide

CAS No: 247062-33-5
Strengths Available: 5mg/10mg/20mg
Format: Sealed containment / vial presentations available
Volume: 3 mL

What This Product Is About

Abaloparatide is a synthetic 34-amino-acid peptide related to parathyroid hormone-related protein (PTHrP). It is mainly associated with bone formation and osteoporosis research.

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Description

What Is Abaloparatide?

Abaloparatide is an N-terminal analogue of human PTHrP and an agonist of the PTH1 receptor. It is a synthetic 34-amino-acid peptide designed to reproduce selected biological actions of naturally occurring PTHrP while producing a clinically useful bone-forming response.



Why Researchers Became Interested in Abaloparatide

Researchers became interested in abaloparatide because it provides a way to study how PTH1 receptor signalling influences bone formation, skeletal strength and bone metabolism

Key Research Focus Areas

  • Bone formation
  • Osteoblast activity
  • Osteoporosis
  • Bone mineral density
  • Fracture prevention
  • PTH1 receptor signalling
  • Bone metabolism

What the Research Has Shown

Research has shown that abaloparatide can increase bone mineral density and reduce the occurrence of certain fractures in people at high risk of osteoporosis-related fractures



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Scientific Background and Research Context
Abaloparatide is a synthetic peptide analogue studied for its activity at the PTH1 receptor, which plays an important role in bone metabolism.

Exploring the Science Behind Abaloparatide
Research focuses on how abaloparatide may influence bone formation, remodelling, and mineral density.

Research Context in Endocrine and Metabolic Science
It is studied in areas including bone metabolism, receptor signalling, and skeletal health.

Ongoing Scientific Interest
Researchers continue to investigate its signalling behaviour and effects on bone-related biological processes.

Ingredient Profile
Single research compound: Abaloparatide
CAS: 247062-33-5
Purity >99%
Supplied as lyophilised powder (no excipients, fillers or additives).

Active Ingredients
Abaloparatide— 5mg/10mg/20mg mg

Ingredient Breakdown

Abaloparatide: 5mg/10mg/20mg of active peptide per vial (lyophilised).

 Why is Abaloparatide studied in metabolic research?
It is studied mainly because of its effects on bone and mineral metabolism, including pathways involved in bone formation and remodelling.

Is Abaloparatide approved for medical use?
Yes. Abaloparatide is an approved prescription medicine for osteoporosis in certain patient groups. Approved indications vary by country.

Why does purity matter so much for this product?
High purity helps ensure that laboratory research is performed with material containing minimal synthesis by-products or unwanted impurities.

What does “research grade” mean?
Research grade means the material is intended for laboratory or analytical research and should not automatically be considered suitable for human use.

Is international supply available?
International supply depends on the supplier, destination country and applicable import and medicines regulations.

Research & laboratory use only. Not for human or veterinary use. Not a medicinal product, supplement, food or medical device. No therapeutic, diagnostic, cosmetic, wellness or lifestyle claims are made or implied. Analytical reference/click information is a laboratory measurement aid only and must not be applied to living systems.

Typically supplied at >99% purity, supported by batch-specific analytical data. UK-based preparation, analysis and release under scientist-led, GMP-aligned processes with full batch-level traceability. Certificate of Analysis (CoA) available on request; independent analytical verification where appropriate.

Store the lyophilised powder refrigerated at 2–8°C, protected from light and moisture; suitable for longer-term storage frozen at -20°C. Handle under appropriate laboratory conditions. For in vitro research use only.

For in vitro laboratory research only. Reconstitution, handling and experimental design at the discretion of the qualified researcher. The 300-click sealed-containment system is an analytical measurement reference only and does not represent dosing or administration guidance. Not for use in living systems.

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